Lupus is an autoimmune disease – the immune system attacks body tissues and cells. New research has cited the root cause of lupus. Adding to the root cause, scientists may be able to deduce a possible cure.
Around 1.5 million people in the USA have Systemic Lupus Erythematous (SLE) or lupus – details shared by the Lupus Foundation of America. What’s more, is the absence of any cure for lupus. However, a recent discovery has raised hopes for the scientific, and the diseased community.
The Research Conducted
The study revolved around comparing 19 SLE-positive patients with non-positive patients. Furthermore, the results were hopeful, thus, determining the root cause.
Adding to the discovery, scientists found excessive production of T cells, activating B cells. Furthermore, an in-depth analysis showed Type 1 interferon modulates, regulating more T cells. Moreover, scientists term this an abnormal activity, so, the immune system attacks its organs.
Research co-author, Karen Costenbader, chairperson of Lupus-Foundation of America’s Medical-Scientific-Advisory Council, is hopeful to take this new fining forward. Adding to the discovery, he explains, “This basic research, uncovering how interferon drives abnormal T and B cell interactions that cause the abnormal autoimmunity of lupus, is really exciting. It was very careful, well-conducted, hypothesis-driven research, which now suggests a new way that we might treat lupus, targeting this abnormal pathway by which a certain type of T cell stimulates B cells, which are the producers of autoantibodies in lupus.”
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A cure is a far-fetched idea, though. However, Karen is hopeful, stating, “We have new drugs for the treatment of lupus because of basic research such as this, uncovering how the T and B lymphocytes interact and identifying new targets for drugs to interrupt abnormal signaling.”
Furthermore, increasing the sample size of the research conducted. Thus, reaching a more accurate result.
